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Volume 36 , Issue 4
July/August 2016
Pages 475–482

Minimally Invasive Surgical Technique in Periodontal Regeneration: A Randomized Controlled Clinical Trial Pilot Study

Carlo Ghezzi, DDS/Luca Ferrantino, DDS, MSc, PhD/Luigi Bernardini, DDS/Margherita Lencioni, DDS/Silvia Masiero, DDS

PMID: 27333004
DOI: 10.11607/prd.2550

The purpose of this study was to compare two minimally invasive surgical techniques (MISTs) for the treatment of periodontal defects: (1) guided tissue regeneration (GTR) using resorbable minimembrane and particulate xenograft (DBBM); and (2) inductive periodontal regeneration (IPR) using enamel matrix derivatives and DBBM. A sample of 20 infrabony periodontal defects in 20 patients were randomly assigned to either the GTR or the IPR group. A followup was performed at 12 months postoperative. Significant improvement in clinical parameters was observed in both groups, although no intergroup differences were found. MIST with GTR or IPR demonstrated very good outcomes 1 year after surgery, with no differences between treatment groups.

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